Wrin'Coat Series
The ExCellness Wrin'Coat wrinkling substrates are designed to provide semi-quantitative information on cell contractile activity.
Fields of application:
- Wrinkling substrates are principally used to visualize and measure contraction of adherent cells in vitro. The mechanical properties of the substrate are adapted to the contractile force of fibroblastic and muscular cells.
- Wrinkling substrates can be used to visualize and measure contraction of tissue samples (e.g. muscle fibers, cross-sectioned blood vessels, contractile glands, organoids, etc.)
- Wrinkling substrates can be used to identify contractile cells in a heterogenous population by combining with immunofluorescence microscopy.
- Wrinkling substrates can be used to measure cell/tissue contraction in response to drug treatments over time, over concentration series, and to compare contraction between conditions (e.g., contractile versus non-contractile fibroblasts).
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